// Axio Management
Lee Hooks, M.B.A., Chief Executive Officer
Mr. Hooks was appointed Chief Executive Officer of Axio Research Corporation in 2001. He is the former CEO of Point of CareWare.com, a Bellevue-based medical software company. Prior to his position at Point of CareWare.com, Mr. Hooks was Executive Director of Providence Health Plan of Washington. He came to Seattle from San Francisco, where he was Vice President of CSC Index, responsible for this management consulting firm's West Coast healthcare practice. He received his MBA from the University of Chicago.
Jon Case, M.B.A, Director of Business Development
Mr. Case is Director of Business Development for Axio Research, LLC. Appointed to this role in 1998, he leads the Axio sales team, develops and guides corporate business strategy, and provides corporate leadership as a member of the Axio Management Team. Additionally, he served as interim CEO of Axio from 2000-2001.
Axio Research is the world leader in planning and managing Data Monitoring Committees; Mr. Case leverages his extensive experience and industry contacts in the Biotechnology and Pharmaceutical industry to assist Axio clients in this area. Additionally, he assists clients in the creation of data management teams, clinical events committees, and medical writing groups.
Prior to joining Axio, he served as Director of Corporate Development for both Koronis Pharmaceuticals and Targeted Genetics Corporation (now AmpliPhi Biosciences Corporation), both biotechnology companies located in Seattle. Mr. Case also served as Director of Business Development for Centocor, Inc. (now Janssen Biotech, Inc.). He received his B.S. and MBA from the Wharton School of the University of Pennsylvania.
Kent Koprowicz, Global Head, Biostatistics
Mr. Koprowicz joined Axio Research in 2009 and was appointed Global Head, Biostatistics in 2012. Mr. Koprowicz has more than a decade of experience as a biostatistician—in managing and directing statistical efforts on NIH-sponsored clinical trials as well as for private clinical and epidemiological research projects in cardiovascular and other disease areas. Mr. Koprowicz is experienced in all phases of clinical trial research, from design and sample size calculations to collaborative authorship of study findings. In addition, he manages and provides statistical support for numerous DMCs (Data Monitoring Committees) on phase 2/3 clinical trials. Mr. Koprowicz holds a Bachelors degree in Mathematics from the University of Colorado and a Master’s degree in Biostatistics from the University of Washington.
Ruth McBride, Scientific Director
Ms. McBride is Scientific Director of Axio. Ms. McBride has more than 20 years’ experience with NIH- and industry-sponsored clinical trials and data management. She was Deputy Director for the Coordinating Centers for the NIH’s Stroke Prevention in Atrial Fibrillation Studies, Cardiac Arrhythmia Suppression Trial, and Antiarrhythmic Versus Implantable Defibrillator trials. In addition, she has served on the Board of Directors for the Society for Clinical Trials and as the co-editor of a special supplement to Controlled Clinical Trials on clinical data management. Ms. McBride holds an Sc.B. in Applied Mathematics from Brown University.
Anna Leonen, Director of Data Management
Ms. Leonen has over 16 years’ experience in clinical trial data management, analysis, and technical reporting. Prior to joining Axio in 2007, Ms. Leonen worked, in different capacities, on several NHLBI and industry-sponsored trials in the areas of cardiology and severe traumatic injury at the University of Washington Clinical Trials Coordinating Center. She began as a research analyst for the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial, and later managed the day-to-day operations of the industry-sponsored Dual-Chamber And VVI Implantable Defibrillator (DAVID and DAVID II) Trials. For the Resuscitation Outcomes Consortium (ROC), Ms. Leonen served as Manager of Data Operations, where she oversaw the implementation of a custom web-based electronic data capture system.
At Axio, she currently supervises the data management staff and serves as project director for NIH and industry-sponsored trials. She has co-authored articles that have been published in journals such as Circulation, Journal of the American College of Cardiology, and Pacing and Clinical Electrophysiology. Ms. Leonen completed a Master of Science degree at Oregon State University where she studied Operations Research and Statistics. She received her B.A. in Mathematics and Economics from Claremont McKenna College.
David Henderson, Ph.D., Director of Statistical Genetics
Dr. David Henderson brings to Axio more than 20 years of experience in genetics, genomics, statistics, and statistical computing. Prior to joining Axio, he provided business consulting services to pharmaceutical and biotechnology companies for experimental design, data analysis, and interpretation of results from genomic and genetic data at LabCorp Clinical Trials, Covance, Sage Bionetworks, and Rosetta Inpharmatics. Dr. Henderson holds a B.Sc. in Animal Science from Texas A&M University, an M.Sc. in Molecular Genetics from South Dakota State University, and a Ph.D. in Statistical Genetics from Virginia Polytechnic Institute and State University.
Bill Coar, Ph.D., Director of Central Operations
Dr. William Coar began his career in the pharmaceutical industry in 1995 as a SAS programmer for a Contract Research Organization in Pennsylvania after graduating from Bloomsburg University. He has since earned a Masters degree in Applied Statistics from Villanova University in May of 2000, followed by a PhD in Statistics from Colorado State University in 2007. Bill joined Axio in January 2010 as a Project Director/Statistician, and is the current Director of Central Region Operations based in Broomfield, Colorado. He is primarily responsible for providing leadership, direction, and oversight for the business development and statistical activities of the company in the Central Region of the United States. He is an active member of the Biopharmaceutical Section of the American Statistical Association, and serves as the Chair of the Denver SAS User Group.
Linda Nealy, Controller
Ms. Nealy was appointed as Axio’s financial controller in 2008. She brings close to two decades of accounting, IT, and HR experience to the firm. At Axio, Ms. Nealy oversees financial accounting and project information systems. Prior to joining Axio, she spent eight years in the financial services sector with Seattle private equity firm Montlake Capital, serving as controller for the last five years. Her other professional experiences include positions within the manufacturing and construction industries, including assistant business manager, personnel administrator, staff accountant, and office manager. Ms. Nealy holds a B.A. in Arts and Sciences from the University of Washington.
Anita Richard, Director of Human Resources
Currently Axio’s Human Resources Director, Ms. Richard has worked with the company’s Human Resources team since 2001. She has 10 years of experience in all aspects of Human Resources issues and development in both the consulting and biotech industries. She has served on the Washington Biotechnology & Biomedical Association's (WBBA) Human Resources Group since 2001. Ms. Richard holds a B.A. in Business and received her national certification as a Professional in Human Resources (PHR) from the Human Resources Certification Institute.
Brian Ingersoll, Director of Information Technology
Mr. Ingersoll joined Axio Research in 2000 and was appointed Project Director in 2002 and Director of Information Technology in 2004. Mr. Ingersoll has more than a dozen years of clinical trial experience, primarily focused on data management, development of custom data collection software, and information technology. In addition, he has directed and managed the data collection for clinical drug and/or device trials as well as numerous QI and PRO projects. These projects range from small, regional Phase 1/2 studies to large, complex, multinational Phase 2/3 studies. Mr. Ingersoll holds a B.S. in Microbiology from the University of Washington.